Home of Smith Brothers Black and Menthol Cough Drops and Triple action Cough Syrup. Points of Interest in Poughkeepsie. First Settled in 1687. • Home of George Clinton, first Governor of New York. • Court House – site of building where the Federal Constitution was ratified in 1788. • Vassar College founded by Matthew Vassar in 1861. • Smith Brothers Cough Drop Factory “Famous since 1847”.